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產品名稱:Thermo抗體代理IL-33 Polyclonal Antibody Pierce抗體供應

產品型號:Pierce抗體 20398

產品報價:

產品特點:Host / Isotype:
RabbitClass:
Polyclonal
Type:
Antibody
Species Reactivity:
Human (Hu) Murine (Ms) Rat
WB

Pierce抗體 20398Thermo抗體代理IL-33 Polyclonal Antibody Pierce抗體供應的詳細資料:

IL-33 Polyclonal Antibody

IL-33 Antibody for Western blot

>> See 3 other antibodies for IL33
Entrez Gene ID:
(Human) 90865
UniProt ID:
O95760
 
Details
   
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Murine (Ms) Rat (Rt)
Immunogen: A 19 amino acid peptide from near the center of human IL-33.
Ordering Information
Pierce IL-33 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
 
PA5-20398 100 ug   Purchase »


Storage: Stored at -20ºC, avoid repeated freeze thaw cycles
Form: 100 ug of affinity chromatography purified antibody (1 mg/ml) in PBS containing 0.02% sodium azide.


 
Applications Dilution *
   
Western Blot (WB) 1 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
 
Product Specific Information
PA5-20398 targets IL-33 in WB applications and shows reactivity with Human, Murine, and Rat samples.

The PA5-20398 immunogen is a 19 amino acid peptide from near the center of human IL-33.
General Information
Interleukin-33 (IL-33) is a recently identified member of the IL-1 family of cytokines whose other members include IL-1-a/beta, IL-1Ra and IL-18. Its receptor has been shown to be ST2, an IL-1 receptor family member that also acts as a negative regulator of TLR-IL-1R signaling and IL-1R accessory protein (IL-1RAcP). Receptor binding of IL-33 activates NF-kappa-B and MAP kinases and induces the expression of TH2-associated cytokines such as IL-4, IL-5 and IL-6. Prolonged IL-33 treatment of mice led to the development of eosinophilia, splenomegaly, and severe pathological changes in mucosal organs such as lungs, esophagus and small intestine. Recent experiments have shown that IL-33 can also co-localize with heterochromatin and possesses transcriptional repressor activities, indicating that IL-33 may function as both a proinflammatory cytokine and an intracellular nuclear factor with transcriptional regulatory properties.
 
Product Images
Filter :
  • WB using PA5-20398
    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    View Product Details >>
    Western blot analysis of IL-33 in human lymph node tissue lysate with IL-33 antibody at (A) 1 and (B) 2 ug/mL.
     
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  •  
  •  
  • WB using PA5-20398
    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    Western Blot with anti-IL-33 Polyclonal Antibody (PA5-20398)

    View Product Details >>
    Western blot analysis of IL-33 in human lymph node tissue lysate with IL-33 antibody at (A) 1 and (B) 2 ug/mL.
     
  •  

 

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